Population Council program, Phase II

As part of its strategy for the introduction of the levonorgestrel-releasing subdermal contraceptive implants NORPLANT and NORPLANT-2 worldwide, in 1986 the Population Council approved a grant to Mexico's National Institute of Nutrition S.Z. to support an expanded Phase III clinical trial on the acceptability and effectiveness of NORPLANT and NORPLANT-2. This report presents obtained during the grant period (9/86-12/89). As previously shown in other populations, the report shows that NORPLANT and NORPLANT II combine high continuation rates and use-effectiveness in preventing pregnancy in Mexican women. The clinical aspects of insertion and removal of the implants introduce an important safety consideration. Appropriate training and supervision of clinic personnel is essential for the safe and effective utilization of this contraceptive method. In the present study as in previous ones, the disturbance of endometrial bleeding patterns seems to be the main problem associated with its particularly during the first 6 months after insertion. Overall, the data show that both NORPLANT and NORPLANT II are highly effective contraceptive methods for the Mexican population and provide wome

Source: DEC abstract, PN-ABH-319 (1990). This is the source's own text, not a cited summary of the documents.